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Grdina, David
One or more keywords matched the following items that are connected to Grdina, David
Item TypeName
Concept CHO Cells
Academic Article Reversion of radiosensitivity in azacytidine-treated XRS5 cells does not result in full radioprotection by WR-1065.
Academic Article Effects of growth media on cell cycle progression in CHO cells exposed to the radioprotector WR-1065.
Academic Article The inhibition of radiation-induced mutagenesis by the combined effects of selenium and the aminothiol WR-1065.
Academic Article Chemical protection and cell-cycle effects on radiation-induced mutagenesis.
Academic Article WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells.
Academic Article Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine.
Academic Article Effects of thiols on topoisomerase-II alpha activity and cell cycle progression.
Academic Article Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity.
Academic Article Relationships between cytoprotection and mutation prevention by WR-1065.
Academic Article Accumulation of CHO cells in G2 phase following exposure to WR-1065.
Academic Article Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells.
Academic Article Inhibition of topoisomerase II alpha activity in CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065).
Academic Article Chromosome terminal deletion formation in Chinese hamster ovary cells.
Academic Article Expression of thymidine kinase messenger RNA and a related transcript is modulated by radioprotector WR1065.
Academic Article Varying levels of radioprotection from the effects of JANUS neutrons in repair-deficient xrs-5 hamster cells treated with azacytidine.
Academic Article The effects of cycloheximide and WR-1065 on radiation-induced repair processes: a mechanism for chemoprevention.
Academic Article Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action.
Academic Article Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278).
Academic Article Radiosensitivity of mammalian cell lines engineered to overexpress cytosolic glutathione peroxidase.
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